147 lines
4.7 KiB
C++
147 lines
4.7 KiB
C++
//
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// ********************************************************************
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// * License and Disclaimer *
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// * *
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// * The Geant4 software is copyright of the Copyright Holders of *
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// * the Geant4 Collaboration. It is provided under the terms and *
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// * conditions of the Geant4 Software License, included in the file *
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// * LICENSE and available at http://cern.ch/geant4/license . These *
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// * include a list of copyright holders. *
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// * *
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// * Neither the authors of this software system, nor their employing *
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// * institutes,nor the agencies providing financial support for this *
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// * work make any representation or warranty, express or implied, *
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// * regarding this software system or assume any liability for its *
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// * use. Please see the license in the file LICENSE and URL above *
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// * for the full disclaimer and the limitation of liability. *
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// * *
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// * This code implementation is the result of the scientific and *
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// * technical work of the GEANT4 collaboration. *
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// * By using, copying, modifying or distributing the software (or *
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// * any work based on the software) you agree to acknowledge its *
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// * use in resulting scientific publications, and indicate your *
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// * acceptance of all terms of the Geant4 Software license. *
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// ********************************************************************
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//
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//
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/// file: DamageModel.hh
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/// brief: Parameters related to the DNA Damage model
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#ifndef MOLECULAR_DAMAGE_MODEL
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#define MOLECULAR_DAMAGE_MODEL
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#include "DamageModelMessenger.hh"
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#include "G4Electron_aq.hh"
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#include "G4Hydrogen.hh"
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#include "G4MolecularConfiguration.hh"
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#include "G4OH.hh"
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#include "G4SystemOfUnits.hh"
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#include "Randomize.hh"
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#include "globals.hh"
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//....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......
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class DamageModel
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{
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public:
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DamageModel();
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virtual ~DamageModel() { delete fpDamageMessenger; };
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// methods
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G4bool IsDirectStrandBreak(const G4double&) const;
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G4bool IsIndirectStrandDamage(const G4MolecularConfiguration*) const;
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G4bool IsIndirectBaseDamage(const G4MolecularConfiguration*) const;
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G4bool IsInducedStrandBreak(const G4MolecularConfiguration*) const;
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// setters
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void SetDirectDamageLower(G4double d)
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{
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fDirectDmgLower = d;
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if (fDirectDmgLower < fDirectDmgUpper) fDirectDmgUpper = fDirectDmgLower;
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};
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void SetDirectDamageUpper(G4double d)
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{
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fDirectDmgUpper = d;
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if (fDirectDmgLower > fDirectDmgUpper) fDirectDmgLower = fDirectDmgUpper;
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};
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// Indirect OH
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void SetIndirectOHStrandChance(G4double d)
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{
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CheckValidProbability("DamageStrandOH", d);
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fStrandOH = d;
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}
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void SetIndirectOHBaseChance(G4double d)
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{
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CheckValidProbability("DamageBaseOH", d);
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fBaseOH = d;
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}
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void SetInductionOHChance(G4double d)
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{
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CheckValidProbability("InductionOH", d);
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fInductionOH = d;
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};
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// Indirect Eaq
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void SetIndirectEaqStrandChance(G4double d)
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{
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CheckValidProbability("DamageStrandEaq", d);
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fStrandEaq = d;
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}
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void SetIndirectEaqBaseChance(G4double d)
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{
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CheckValidProbability("DamageBaseEaq", d);
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fBaseEaq = d;
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}
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void SetInductionEaqChance(G4double d)
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{
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CheckValidProbability("InductionEaq", d);
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fInductionEaq = d;
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};
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// Indirect H
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void SetIndirectHStrandChance(G4double d)
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{
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CheckValidProbability("DamageStrandH", d);
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fStrandH = d;
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}
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void SetIndirectHBaseChance(G4double d)
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{
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CheckValidProbability("DamageBaseH", d);
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fBaseH = d;
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}
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void SetInductionHChance(G4double d)
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{
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CheckValidProbability("InductionH", d);
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fInductionH = d;
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};
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protected:
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static void CheckValidProbability(const G4String& str, G4double p);
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private:
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DamageModelMessenger* fpDamageMessenger;
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G4double fDirectDmgLower = 17.5 * eV, fDirectDmgUpper = 17.5 * eV;
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G4double fInductionOH = 0, fInductionEaq = 0, fInductionH = 0;
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G4double fStrandOH = 1.0, fStrandEaq = 1.0, fStrandH = 1.0;
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G4double fBaseOH = 1.0, fBaseEaq = 1.0, fBaseH = 1.0;
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const G4MoleculeDefinition* fOH = G4OH::Definition();
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const G4MoleculeDefinition* fe_aq = G4Electron_aq::Definition();
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const G4MoleculeDefinition* fH = G4Hydrogen::Definition();
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};
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//....oooOO0OOooo........oooOO0OOooo........oooOO0OOooo........oooOO0OOooo......
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#endif // MOLECULAR_DAMAGE_MODEL
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