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geant4/examples/advanced/dna/dsbandrepair/analysis/include/AnalysisHandler.hh
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2024-12-06 11:11:40 +01:00

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/// \file AnalysisHandler.hh
/// \brief Definition of the AnalysisHandler class
#ifndef AnalysisHandler_h
#define AnalysisHandler_h 1
#include <memory>
#include "ScanDamage.hh"
#include "TLKModel.hh"
#include "LEMIVModel.hh"
#include "BelovModel.hh"
class AnalysisHandler
{
public:
AnalysisHandler(/* args */);
~AnalysisHandler() = default;
void SetThresholdEnergy(double e);
void GetAllDamageAndScanSB();
void GiveMeSBs();
void ApplyDNAModel(const std::string dnamodel);
void SetBpForDSB(unsigned int pVal);
void SetParametersForTLKModel(double pLambda1 = 3.0,double pLambda2=0.03,
double pBeta1=0.01, double pBeta2=0.06,double pEta=0.002);
void SetParametersForLEMIVModel(double pLoopLength=2e6,double pFunrej=0,
double pTfast=0.24,double pTslow=2.81);
void CreateSDD(std::string filename);
private:
///void GetDoseFromEdep();
std::unique_ptr<ScanDamage> fScanDamage;
std::unique_ptr<TLKModel> fTLKModel;
std::unique_ptr<LEMIVModel> fLEMIVModel;
std::unique_ptr<BelovModel> fBelovModel;
std::vector<Damage> fAllDamage;
std::pair<float,float> fNsDSBandError = {0,0};
std::pair<float,float> fNcDSBandError = {0,0};
std::pair<float,float> fNDSBandError = {0,0};
std::pair<float,float> fNDSBdirandError = {0,0}; // DSB has contribution from at least one direct damage
std::pair<float,float> fNDSBIndandError = {0,0}; // DSB has contribution from at least one indirect damage
std::pair<float,float> fNDSBdirIandError = {0,0}; // DSB has contribution from both direct and indirect damage
std::pair<float,float> fNSSBandError = {0,0};
std::pair<float,float> fNSBandError = {0,0};
std::pair<float,float> fNdirSBandError = {0,0};
std::pair<float,float> fNindirSBandError = {0,0};
bool fIsSBScanned = false;
// num of bp to consider a DSB for the MakeCluster function
// default value is 10
unsigned int fBpForDSB{10};
// store dose deposited in nucleus cell
double fDose{0};
//TLK: Compute a SF Curve
double pTLKDoseMax{0}, pTLKDeltaDose{0};
//LEMIV: compute fraction of unrejoined DSB up to pLEMIVTimeMax (h) and pLEMIVDeltaTime steps
double pLEMIVtimeMax{0}, pLEMIVdeltaTime{0};
double fNBp{0};// number of base pairs
double fEdepInNucleus{0}; // eV
double fNucleusVolume{0};
std::map<int,unsigned long long int> fChromosomeBpMap; //Store number of Bp in each Chomosomes;
};
#endif