Import Geant4 10.5.0 source tree
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Gabriele Cosmo
@@ -7,7 +7,7 @@
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---------------------
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The brachytherapy example is currently maintained and upgraded by Susanna Guatelli (1) and Dean Cutajar (1), with the support of
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The brachytherapy example is currently maintained and upgraded by Susanna Guatelli (1), Albert Le (1) and Dean Cutajar (1), with the support of
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Luciano Pandola (2)
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1. Centre For Medical Radiation Physics (CMRP), University of Wollongong, NSW, Australia.
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@@ -29,7 +29,7 @@ S. George, S. Agostinelli, F. Foppiano, S. Garelli, M. G. Pia, M. Tropeano
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Brachytherapy example simulates the energy deposit in a water phantom, produced by:
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1) Iridium sources (Flexisource and TG186).
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2) Iodine source (Bebig Isoseed I-125).
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2) Iodine sources (Bebig Isoseed and Oncura 6711 I-125).
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3) Leipzig Applicator with an iridium source (model from the Istituto Tumori, Genova, Italy).
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The Flexisource, an Ir-192 source manufactured by Nucletron, an Elekta company, is a source commonly used for high dose rate brachytherapy treatments.
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@@ -49,16 +49,19 @@ In particular in this example it is shown how to:
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- define the physics by means of a Geant4 Modular Physics List
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- save results in an analysis ROOT file
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- calculate the dose rate distribution along the main axis of the source
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- compare the calculated dose rate distribution to reference data. In the case of the example, the dose rate
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distribution of a Flexisource is compared to D. Granero, J. Pérez-Calatayud, E. Casal, et al,
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"A dosimetric study on the Ir-192 high dose rate Flexisource", Med. Phys. 33 (12), 2006, 4578-82.
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- compare the calculated dose rate distribution to reference data.
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In the case of the example, the dose rate distribution of a Flexisource is compared to D. Granero,
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J. Pérez-Calatayud, E. Casal, et al,"A dosimetric study on the Ir-192 high dose rate Flexisource", Med. Phys. 33 (12), 2006, 4578-82.
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The dose rate distribution of the Oncura 6711 I-125 source is compared to J. Dolan, Z. Lia, J. F. Williamson, "Monte Carlo and experimental
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dosimetry of an I-125 brachytherapy seed", Med. Phys. 33(12), 2006.
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The example can be executed in multithreading mode.
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------------------------------------------------------------------------
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----> 1.Experimental set-up.
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The default source is a Ir-192 Flexisource set in the center of a water phantom with size 30 cm.
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The default source is a Ir-192 Flexisource set in the center of a water phantom with size 30 cm.
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The phantom is set in the World volume filled with air.
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The primary radiation field is defined by means of the GeneralParticleSource
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@@ -79,10 +82,12 @@ The installation of ROOT is required (http://root.cern.ch/drupal/).
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----> 3.How to run the example.
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- Batch mode:
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$G4WORKDIR/bin/Linux-g++/Brachy FlexiSourceMacro.mac
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$G4WORKDIR/bin/Linux-g++/Brachy FlexiSourceMacro.mac
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$G4WORKDIR/bin/Linux-g++/Brachy LeipzigSourceMacro.mac
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$G4WORKDIR/bin/Linux-g++/Brachy IridiumSourceMacro.mac
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$G4WORKDIR/bin/Linux-g++/Brachy IodiumSourceMacro.mac
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$G4WORKDIR/bin/Linux-g++/Brachy LeipzigSourceMacro.mac
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$G4WORKDIR/bin/Linux-g++/Brachy IodiumSourceMacro.mac (model of the Bebig Isoseed I-125)
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$G4WORKDIR/bin/Linux-g++/Brachy OncuraIodineSourceMacro.mac (model of the Oncura 6711 I-125)
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$G4WORKDIR/bin/Linux-g++/Brachy LeipzigSourceMacro.mac
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- Interative mode:
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3) $G4WORKDIR/bin/Linux-g++/Brachy
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@@ -104,16 +109,16 @@ iodine_source_primary.mac and iridium_source_primary.mac
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2) Model the radioactive Decay. The primary particle is the radionuclide.
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This option is modelled in iodine_decay.mac and TG186_iridium_decay.mac
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The GPS macros are executed in VisualisationMacro.mac 9default, FlexiSourceMacro.mac, IodineSourceMacro.mac, LeipzigSourceMacro.mac
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The GPS macros are executed in VisualisationMacro.mac by default, FlexiSourceMacro.mac, IodineSourceMacro.mac, LeipzigSourceMacro.mac
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- The Flexisource is the default source of the example.
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- In VisualisationMacro.mac the source is the default one. iridium_source_primary.mac is executed to define the radiation field emerging from the iridium core.
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- In FlexiSourceMacro.mac the Flexi ir source geometry is selected via interactive command. The radiation field is defined in the iridium_source_primary.mac.
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- In FlexiSourceMacro.mac the Flexi Ir source geometry is selected via interactive command. The radiation field is defined in the iridium_source_primary.mac.
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- In IodineSourceMacro.mac, the Bebig Isoseed I-125 brachytherapy source is modelled. The radiation field is modelled in terms of emitted photons in iodine_source_primary.mac.
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Alternatively the radioactive decay of I can be modelled using teh macro iodine_decay.mac.
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- In LeipzigSourceMacro.mac, A Leipzig applicator (design provided by Istituto Tumori, Genova) is modelled. The iridium_source_leipzig_primary.mac defines the radiation field of the Ir core.
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- The TG186SourceMacro.mac models the reference bIr brachytherapy source. The radiation field can be either defined with the iridium_source_primary.mac (spectrum of the emitted photons) or with TG186_iridium_decay.mac (model of the Ir decay).
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- OncuraIodineSourceMacro.mac models both the geometry and the radioactive decay of the Oncura 6711 I-125 source.
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--------------------------------------------------------------------------------
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----> 5. Physics List
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@@ -141,9 +146,10 @@ The output is:
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By default:
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EnergyDeposition_Flexi.out contains the Edep when the Flexi source is selected.
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EnergyDeposition_iodine.out contains the Edep when Iodine source is selected.
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EnergyDeposition_iodine.out contains the Edep when Iodine Bebig Isoseed source is selected.
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EnergyDeposition_TG186.out contains the Edep when the TG186 source is selected.
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EnergyDeposition_Leipzig.out contains the Edep when the Iridium source with Leipzig applicator is selected.
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EnergyDeposition_Oncura.out contains the Edep when the Iodine Oncura 6711 source is selected.
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- brachytherapy.root, containing
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- a 2D histogram with the energy deposition in the phantom. The macro macro.C is provided as example
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@@ -151,7 +157,7 @@ The output is:
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The ROOT file will be created if the example is built with the WITH_ANALYSIS_USE=ON option (see section 2).
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- 1D histogram withe the plot of energy spectrum of gamma emitted by the radioactive decay when gamma are generated directly as
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primary particles or whenthey derive from Radioactive Decay(see section 4).
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plot_primary.C is provided as example to open brachytherapy.root and to plot the energy spectra
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plot_primary.C is provided as example to open brachytherapy.root and to plot the energy spectra
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-------------------------------------------------------------------------------
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----> 8.Visualisation
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@@ -167,13 +173,12 @@ in the brachytherapy.root file.
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The ROOT macro TG43_relative_dose.C has brachytherapy.root as input file. It calculates the dose rate distribution along the main axis of
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the brachytherapy source. The dose rate is normalised to 1 at 1 cm distance from the centre.
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The output file is geant4_dose.txt with two columns:
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distance from the centre (cm) dose rate distribution
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distance from the centre (cm) dose rate distribution
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The user can then compare the dose rate distribution calculated with the example to reference data.
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Directory "comparison":
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As an example, the dose rate distribution calculated with the Flexisource is compared to reference data from D. Granero, J. Pérez-Calatayud, E. Casal, et al,
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"A dosimetric study on the Ir-192 high dose rate Flexisource", Med. Phys. 33 (12), 2006, 4578-82.
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As an example, the dose rate distribution calculated with the Flexisource is compared to reference data from D. Granero, J. Pérez-Calatayud, E. Casal, et al, "A dosimetric study on the Ir-192 high dose rate Flexisource", Med. Phys. 33 (12), 2006, 4578-82.
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The compare.C is a ROOT macro which reads the dose rate distribution calculated with the Flexisource (geant4.txt generated with the advanced example and 280 M histories ) against the reference.
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@@ -182,3 +187,8 @@ The directory "comparison" contains:
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- the data obtained in Geant4.10.3: geant4.txt, 280 M events. geant4.txt is obtained when executing the macro TG43_relative_dose.C
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- comparison.C - macro to read geant4.txt and granero.txt and compare them in the same plot
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-----> 10. Regression testing of Geant4
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- the macros to run are in test_macro
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- the results should be processed with analysis.C
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